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Current Research Projects

Sponsored Research Projects Currently Active

PI Name Project Title Funding Agency Campus
Age related changes in cardiac stem cells and their relation to functional outcomes University of Tampa (Auburn University) Auburn Campus
Assessment of the efficacy and economy of an employer-based biometric screening program as a platform for diabetes prevention UAB Center for Clinical and Translational Science Auburn Campus
Biomechanical basis of pediatric mTBI due to sports related concussion NIH (Virginia Tech) Virginia Campus
Development and pharmacological characterization of mechanistically distinct NMDA receptor allosteric modulators American Heart Association Virginia Campus
Development, implementation and assessment of an interprofessional education program: Identification of best practices AACOM Carolinas Campus
DOD-NCAA Grand Challenge: Concussion assessment, research and education (CARE) consortium NCAA/DOD (Virginia Tech) Virginia Campus
Effects of quaternary ammonium disinfectants on gut microbiota and developmentof immune function Center for One-Health Research Virginia Campus
Exploring the beneficial mechanisms of gemmotherapy-treated peripheral vascular disease using theischemic hind-limb mouse model Center for One-Health Research Virginia Campus
Genetic markers for responders to dofetilide therapy in persistent atrial fibrillation Carilion Clinic Virginia Campus
Healthy Citizens Pulaski County: Implementing chronic disease programs including promoting physical activity and healthy eating Virginia Foundation for Healthy Youth (New River Health District/Pulaski County Health Department) Virginia Campus
Lyme disease in humans and dogs Center for One-Health Research Virginia Campus
MRI: Acquisition of a Force-measuring treadmill for biomedical experimentation and assistive device development National Science Foundation (Virginia Tech) Virginia Campus
Nanoparticles to deliver antisense nucleic acid constructs as therapeutics for intracellular bacterial infections Center for One-Health Research Virginia Campus
Nanotrap tick-panel test development Virginia Biosciences Health Research Corporation (Virginia Tech) Virginia Campus
Neurophysiological effects of whole coffee fruit concentrate in older adults with mild cognitive impairment: a fMRI investigation FutureCeuticals Auburn Campus
Quantification and qualification of stem cells after peripheral mobilization and harvest for orthopaedic point of care applications Arthrex Auburn Campus
The antiglycemic effects of a lower pressure external pneumatic compression device in type II diabetics: a molecular and applied investigation American Diabetes Association Auburn Campus
The Cherokee and Spartanburg County outreach initiative (CSCOI) Appalachian Regional Commission Carolinas Campus
The contribution of NLR proteins in modulating gastrointestinal inflammation following exposure to wheat gluten Center for One-Health Research Carolinas Campus
The effects of a pre-workout supplement on markers of fiber recruitment and muscular fatigue Maximum Human Performance, LLC Auburn Campus
The effects of curcumin on nutritionally induced non-alcoholic fatty liver disease and non-alcoholic steatohepatitis DolCas (Auburn University) Auburn Campus
The effects of red spinach extract on variables related to blood flow and exercise performance Dolcas Auburn Campus
The role of target inflation pressures on skeletal muscle gene expression and the efficacy of a peristaltic pulse external pneumatic compression device as an adjuvant to exercise training. NormaTec Auburn Campus
The role of tri-heteromeric NMDA receptors in stroke and its mitigation Center for One-Health Research Virginia Campus
Use of the the lymphatic pump technique as a novel therapy for IBD American Osteopathic Association Carolinas Campus
VCOM advanced suturing course for residents Ethicon Virginia Campus
Via bioinformatics and clinical genetics network Via-Bradley College of Engineering Foundation Virginia Campus

Biomedical Research

PI Name Project Title Campus
A morphologic and T2 mapping score of the anterior cruciate ligament: Developing an outcome score for the evaluation of ACL reconstructions Auburn Campus
Acute effects of OxySport on lipolysis and basal metabolic rate, as well as chronic effects of OxySPORT on body composition in overweight, college-aged males Auburn Campus
Aging and gender in cardiac and cardiovascular disease Virginia Campus
Analysis of the intracellular interaction of estradiol receptors and sex hormone binding globulin Auburn Campus
Antigen presentation and immune cell viability in simulated microgravity Carolinas Campus
Are quat disinfectants developmental or reproductive toxins? Virginia Campus
Assessing the effectiveness of clinical case studies supplementing Block 1 genetics lectures Carolinas Campus
Biochemical effects of OMM at the cellular level Virginia Campus
Cerium Oxide nanoparticles in the treatment of traumatic brain injury Virginia Campus
CRISPR engineered cardiomyocytes to model Danon disease, a lysosomal cardiomyopathy Carolinas Campus
Development of a nosocomial bacterial vaccine Virginia Campus
Development of a point-of-care diagnostic kit for bacterial and viral pneumonia Virginia Campus
Developmental immunotoxicity of quat disinfectants Virginia Campus
Editing volume of steroids Auburn Campus
Effect of a gluten-free diet on immunity in a DSS colitis model Carolinas Campus
Effect of boron on UV-induced skin cancer Virginia Campus
Effect of Ebola virus proteins, secreted glycoprotein and viral protein 40, upon natural killer cell function Carolinas Campus
Effect of Ebola virus secreted glycoprotein upon macrophage polarization and function Carolinas Campus
Effect of unilateral external pneumatic compression on bilateral measures of skin temperature and regional blood flow Auburn Campus
Effects of a ketogenic diet on bone health Auburn Campus
Effects of a purported thermogenic nutraceutical on changes in body composition and metabolism Auburn Campus
Effects of a subchronic ketogenic diet on skeletal muscle anabolic and catabolic signaling and adipose tissue signaling Auburn Campus
Effects of aging and nutrition on systemic stem cell content and physiological systems Auburn Campus
Effects of aging on systemic stem cell content and tissue functionality Auburn Campus
Effects of chronic testosterone and trenbolone enanthate on mature myostatin protein expression, skeletal muscle hypertrophy and satellite cell number Auburn Campus
Effects of chronic testosterone and trenbolone treatment on markers of skeletal muscle ribosome biogenesis Auburn Campus
Effects of egg protein + colostrum blends on immune cell recovery after dexamethasone-induced immunosuppression in rats Auburn Campus
Effects of simulated microgravity upon human pancreatic cancer cell growth and resistance to natural killer cell cytotoxicity Carolinas Campus
Elucidating the molecular mechanisms of cranial osteopathic manipulation Virginia Campus
Evaluate the effectiveness of the lymphatic pump technique on immunity in a DSS colitis model Carolinas Campus
Evaluation of respiratory syncytial virus pathogenesis Virginia Campus
Examining brain changes associated with a 30-day diet intervention (Whole30 Diet) Auburn Campus
Exploring the cellular mechanisms of toxicity of noradrenochrome and adrenochrome on endothelial cells Carolinas Campus
Fc chimera cancer vaccine for the prevention and immunotherapy of cancer Carolinas Campus
Function, evaluation and applications of mosquito specific smRNAs Virginia Campus
GUY-1 conferred female lethality: Mechanism and application for mosquito control Virginia Campus
Identification of transgenerational methylome changes from disinfectant Virginia Campus
Identifying molecular determinants of novel drug target in NMDA receptors Virginia Campus
Impact of simulated microgravity upon tumor development in vivo Carolinas Campus
Investigating calcium mobilization in estradiol stimulated NGF differentiated PC-12 cells and the interaction between intracellular SHBG and cytoplasmic estradiol receptors (ER_ and ER_) Carolinas Campus
Investigating the effectiveness of an Interprofessional Education curriculum on student attitudes toward interprofessional collaboration Carolinas Campus
Investigating the role of antioxidants in attenuating noradrenochrome and adrenochrome toxicity and cell death Carolinas Campus
IPSC cells from human blood to model X-linked intellectual disability: A collaboration with Greenwood Genetics Carolinas Campus
Making intestinal organoids from induced pluripotent stem cells Carolinas Campus
Modification in sedentary behavior and its influence on blood glucose response Auburn Campus
Molecular mechanism of calcium transport in the heart Virginia Campus
Natural killer cell and T cell function in simulated microgravity Carolinas Campus
NMDA receptor subunit specific drug discovery Virginia Campus
Optimization of bone marrow derived porcine mesenchymal stem cells harvest and cell characterization Auburn Campus
Patient derived human induced stem cell (iPSC) models of Gaucher Type 2, a neurodevelopmental disease Carolinas Campus
Peripheral blood flow and exercise intolerance in pulmonary arterial hypertension Auburn Campus
Role of bone blood flow in bone loss following spinal cord injury Auburn Campus
Role of LGR5 signaling in skeletal muscle myoblast cells (skMDC) Carolinas Campus
Role of mitochondrial supercomplexes in PAH-induced exercise intolerance Auburn Campus
Role of SHBG in calcium influx in PC12 cells Auburn Campus
Role of skeletal muscle arterioles in exercise intolerance in idiopathic pulmonary arterial hypertension Auburn Campus
Screening tap water for development and reproductive toxicants Virginia Campus
Studying the efficacy of 'BCAA 3.1.2' on cycling performance, body composition, and immune system markers in elite cyclists over a training season Auburn Campus
The contribution of NLR proteins in modulating gastrointestinal inflammation following exposure to wheat gluten Carolinas Campus
The effect of microgravity on macrophage differentiation and polarization Carolinas Campus
The effects of different protein and amino acid supplements on muscle hypertrophy after 12 weeks of resistance training in untrained men Auburn Campus
The Role of Indole 2,3-Dioxygenase in Brucella pathogenesis Virginia Campus
The Role of Indole 2,3-Dioxygenase in Brucella pathogenesis Virginia Campus
Variations of human vasculature Carolinas Campus

Clinical Research

PI Name Project Title Campus
A prognostic study of sentinel lymph node micro metastases in women with clinical T1 or T2 NO MO breast cancer Virginia Campus
Atypical presentation of anterior ankle impingement in high jumper Virginia Campus
BATIDAV: Berberine adjunct treatment in Diabetes and vascular disease Virginia Campus
Comparing nitrous oxide spirometry and peak flow for the management of exercise induced bronchospasms and asthma Auburn Campus
Detecting clinically significant cardiac abnormalities with pre-participation ECGs in college athletes Virginia Campus
Differences in participant recall and preference based on patient medication information format Auburn Campus
Effectiveness of noninvasive ventilator modes of respiratory support for infants and children with acute bronchiolitis Carolinas Campus
Environmental impact on testosterone changes in male medical students Virginia Campus
Evaluation of lumbar puncture assist tool (LPAT) as a guide and training tool for successful lumbar puncture Carolinas Campus
Examine and characterize a novel primo-vascular system and to assess the correlation with the principles of osteopathic manipulative medicine Auburn Campus
Gender differences in the performance response to brace wear following ACL reconstruction Virginia Campus
Healing rate of LE ulcers using lymphatic techniques Carolinas Campus
Iron grip strengthening device for rehabilitation, injury prevention and athletic improvement Virginia Campus
Iron supplementation and performance in Division I Athletes Virginia Campus
Non-conformity in the naming of the duodenum and the effect on surgical care Auburn Campus
OMM diagnosis and treatment protocol for pregnant patients with back pain Carolinas Campus
Pediatric Lyme disease in Southwest Virginia Virginia Campus
Pilot Study: Novel therapeutic strategies for treatment of Alzheimer disease Virginia Campus
PolyMA adjunct myeloma study Virginia Campus
Potential damage to nerve cells due to antibodies from a patient infected with Lyme disease Virginia Campus
Prolotherapy, a novel use in Ehlers-Danlos syndrome with multidirectional Instability Virginia Campus
Standardized blood glucose control in non-critically ill patients is associated with a decreased length of stay Carolinas Campus
The effect of osteopathic manipulative treatment on golf swings as measured by driver distances Carolinas Campus
The relationship of pediatric obesity and non-pandemic influenza Carolinas Campus
Undetected Lyme disease in populations in Southwest Virginia, leading to delayed treatment and an increased incidence of chronic infection Virginia Campus
Valgus extension overload in young gymnast leading to osteochondritis dissecans of the left capitellum Virginia Campus
VCOM orthopedic sports medicine research initiative Auburn Campus
Voluntary cough as a treatment adjunct for counterstrain and other myofascial release techniques Carolinas Campus

Educational Research

PI Name Project Title Campus
2nd year osteopathic medical students’ exposure to a community health assessment and intervention project Virginia Campus
A comparison of medical student versus preceptor evaluation of clinical presentation skills Carolinas Campus
A self-directed approach to evaluating procedural skills competency during the first two years of osteopathic medical school Carolinas Campus
Are higher levels of intrinsic motivation related to higher levels of class performance in medical students? Carolinas Campus
Assessing the effectiveness of a Summer Enrichment Program in science and medicine for high school students Carolinas Campus
Case-based interdisciplinary teaching in the preclinical years; a preliminary study on student’s ability to integrate information Carolinas Campus
Development of Pathoma-like board review product Carolinas Campus
Diagnostic experiences of 3rd and 4th year medical students on clinical rotations Virginia Campus
Does computer note-taking have any effect on retention vs. manual note taking in human gross anatomy? Carolinas Campus
Does pre-clinical pediatric experience improve competence and/or confidence in performance during 3rd year pediatric rotations? Carolinas Campus
From cadavers to cases: Using adult learning theories to enhance the laboratory environment Virginia Campus
Gender differences in the use of electronic asynchronous learning tools in osteopathic medical education Virginia Campus
Improvement of througthput of plastinated human organs Virginia Campus
Is student performance is negatively affected by rotating dissection teams? Carolinas Campus
Joint research project on necrotizing periodontal diseases in children Virginia Campus
Pathology consultation in the gross anatomy lab Auburn Campus
Reliability of standardized patient graders versus faculty in a clinical procedural skills assessment in undergraduate medical education Virginia Campus
Retrospective study on performance on standardized patient testing in medical students with mission trip experience vs those without Virginia Campus
The effect of prior knowledge priming, progressive information release, and interrogative questions on the efficiency and effectiveness of student learning Virginia Campus
The effect of required academic support services on academic performance in the medical school setting Virginia Campus
The effects of osteopathic medical school on medical student posture Carolinas Campus
The efficiency and efficacy of integrated multidisciplinary learning modules that contain active learning components Virginia Campus
Using infectious disease modules to increase collaboration by faculty and students Carolinas Campus
Utilization of a web-based training curriculum to improve student knowledge, comfort, and preparation to perform clinical activities required in an advanced pharmacy practice rotation Auburn Campus
Utilizing early pediatric growth to predict the incidence of obesity at 7 years of age Carolinas Campus

Outreach and Other Research

PI Name Project Title Campus
Application of low cost prosthetic devices in Tegucigalpa, Honduras and surrounding areas Virginia Campus
Assessment of hygiene, water accessibility and sanitation in Santa Rosa de Copan, Honduras Virginia Campus
Assessment of the efficacy and economy of an employer-based biometric screening program as a platform for diabetes prevention Auburn Campus
Determination of weaning foods used in the Dominican Republic, El Salvador and Honduras and the impact they have upon gastrointestinal parasitic infections in children Virginia Campus
Effectiveness of educational intervention in medically underserved communities Carolinas Campus
Effectiveness of health fairs in the Hispanic community Carolinas Campus
El Salvador: Exploring barriers to cervical cancer screening Carolinas Campus
Health status of populations in coal mining communities in the Appalachian region of Virginia and West Virginia Virginia Campus
Impact of a diabetes prevention initiative in a rural patient population with prediabetes identified through an employer based screening program Auburn Campus
Impact of a diabetes prevention initiative in patients with prediabetes identified through an employer-based screening program Auburn Campus
Improving diabetic retinopathy screening for the indigent population of Spartanburg, SC Carolinas Campus
Infectious disease assessment in the Caribbean and Central America Virginia Campus
Learning to PLAY! Promoting lifelong activity in youth to prevent pediatric obesity through a holistic intervention at an elementary school in South Carolina Carolinas Campus
Preventive health: Evaluating core strength, symmetry, somatic dysfunction, and injury prevalence among emergency medical personnel Carolinas Campus
Rates of heart disease, cancer, diabetes and obesity in coal production communities in economically distressed areas of Virginia and West Virginia in central Appalachia Virginia Campus
Retrospective study of amputee patient demographic assessment in Tegucigalpa, Honduras and surrounding areas Virginia Campus
Risk factors for cervical cancer in Tegucigalpa, Honduras Carolinas Campus
Survey of clinical encounters and demographics in Veron, Dominican Republic Virginia Campus
Survey of nutrition program support and community development in Honduras Virginia Campus
The prevalence of dermatological infections found in the Dominican Republic, El Salvador, Honduras and rural Appalachia Virginia Campus
Utilization of SAM (an integrated electronic, web-based disease management platform) to improve clinical and humanistic outcomes among obese patients enrolled in an employer-sponsored weight loss program Auburn Campus
VCOM community environment assessment in community centers and an orphanage in Tegucigalpa, Honduras Virginia Campus
VCOM passport to health project Virginia Campus