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Pawel Michalak, PhD

Michalak, Pawel
Pawel Michalak, PhD
Associate Dean for Biomedical Affairs and Research
Department/Discipline: Biomedical Affairs and Research
Campus: Louisiana
Office: 335
Email: Contact
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Research Interests

Professor and Associate Dean for Biomedical Affairs & Research at VCOM-LC focusing on comparative genomics, bioinformatics, and One Health; head of the Integrative Genome Analysis Lab (IGAL) at the Center for One Health Research. His team has employed an integrative approach with a variety of molecular, computational, and modeling techniques, including NextGen sequencing of entire genomes, epigenomes, and transcriptomes to a rigorous understanding of how complexity elaborates from genomes through gene regulatory networks, and how it evolves over generations in response to environmental stress and intragenomic challenges. He worked in nine universities in four countries across three continents. His research resulted in a book (another is in preparation), multiple book chapters, and about 80 peer-reviewed papers in scientific journals, including “Science”, “Nature”, and “Cell”, already cited about 3,000 times and popularized by various public media.



Year University Degree
2003 Louisiana State University  Postdoc
2002 University of Chicago Postdoc
2000 University of Haifa, Israel Postdoc
2000 University of Bialystok, Poland Postdoc
1997 Jagiellonian University, Cracow, Poland PhD-Biology 
1993 Unversity of Lodz, Poland MS-Biology

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Selected Publications

Year Faculty Citation PMID
2021 Lin Kang, Pawel Michalak

Kang L, He G, Sharp AK, Wang X, Brown AM, Michalak P, Weger-Lucarelli J. A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation.  Cell. 2021 Aug 19;184(17):4392-4400.e4. PMID: 34289344.

2020 Pawel Michalak, Lin Kang

Gemmell NJ, Rutherford K, Prost S, Tollis M, Winter D, Macey JR, Adelson DL, Suh A, Bertozzi T, Grau JH, Organ C, Gardner PP, Muffato M, Patricio M, Billis K, Martin FJ, Flicek P, Petersen B, Kang L, Michalak P, Buckley TR, Wilson M, Cheng Y, Miller H, Schott RK, Jordan MD, Newcomb RD, Arroyo JI, Valenzuela N, Hore TA, Renart J, Peona V, Peart CR, Warmuth VM, Zeng L, Kortschak RD, Raison JM, Zapata VV, Wu Z, Santesmasses D, Mariotti M, Guigó R, Rupp SM, Twort VG, Dussex N, Taylor H, Abe H, Bond DM, Paterson JM, Mulcahy DG, Gonzalez VL, Barbieri CG, DeMeo DP, Pabinger S, Van Stijn T, Clarke S, Ryder O, Edwards SV, Salzberg SL, Anderson L, Nelson N, Stone C; Ngatiwai Trust Board. The tuatara genome reveals ancient features of amniote evolution. Nature. 2020 Aug;584(7821):403-409. PMID: 32760000.

2019 Lin Kang, Pawel Michalak, Ramu Anandakrishnan, Robin Varghese

Kinney N, Titus-Glover K, Wren JD, Varghese RT, Michalak P, Liao H, Anandakrishnan R, Pulenthiran A, Kang L, Garner HR. CAGm: a Repository of Germline Microsatellite Variations in the 1000 Genomes Project, Nucleic Acids Res. 2019 Jan 8;47(D1):D39-D45. PMID: 30329086.

2019 Lin Kang, Pawel Michalak, James Mahaney

Kang L, Rashkovetsky E, Michalak K, Garner HR, Mahaney JE, Rzigalinski BA, Korol A, Nevo E, Michalak P. Genomic divergence and adaptive convergence in Drosophila simulans from Evolution Canyon, Israel. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11839-11844. PMID: 31127048.

2017 Lin Kang, Pawel Michalak

Yablonovitch AL, Fu J, Li K, Mahato S, Kang L, Rashkovetsky E, Korol AB, Tang H, Michalak P, Zelhof AC, Nevo E, Li JB. Regulation of gene expression and RNA editing in Drosophila adapting to divergent microclimates. Nat Commun. 2017 Nov 17;8(1):1570. PMID: 29146998.

2014 Katarzyna Michalak, Lin Kang, Pawel Michalak

Kim YB, Oh JH, McIver LJ, Rashkovetsky E, Michalak K, Garner HR, Kang L, Nevo E, Korol AB, Michalak P. Divergence of Drosophila melanogaster repeatomes in response to a sharp microclimate contrast in Evolution Canyon, Israel. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10630-5. PMID: 25006263.

2013 Katarzyna Michalak, Pawel Michalak

Hübner S, Rashkovetsky E, Kim YB, Oh JH, Michalak K, Weiner D, Korol AB, Nevo E, Michalak P. Genome differentiation of Drosophila melanogaster from a microclimate contrast in Evolution Canyon, Israel. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21059-64. PMID: 24324170.

2008 Pawel Michalak

Malone JH, Michalak P. Physiological sex predicts hybrid sterility regardless of genotype. Science. 2008 Jan 4;319(5859):59. PMID: 18174434.