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Pawel Michalak, PhD

Michalak, Pawel
Pawel Michalak, PhD
Associate Dean for Biomedical Affairs and Research
Department/Discipline: Biomedical Affairs and Research
Campus: Louisiana
Office: 335
Email: Contact
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Research Interests

Professor and Associate Dean for Biomedical Affairs & Research at VCOM-LC focusing on comparative genomics, bioinformatics, and One Health; head of the Integrative Genome Analysis Lab (IGAL) at the Center for One Health Research. His team has employed an integrative approach with a variety of molecular, computational, and modeling techniques, including NextGen sequencing of entire genomes, epigenomes, and transcriptomes to a rigorous understanding of how complexity elaborates from genomes through gene regulatory networks, and how it evolves over generations in response to environmental stress and intragenomic challenges. He worked in nine universities in four countries across three continents. His research resulted in a book (another is in preparation), multiple book chapters, and about 80 peer-reviewed papers in scientific journals, including “Science”, “Nature”, and “Cell”, already cited about 3,000 times and popularized by various public media.



Year University Degree
2003 Louisiana State University  Postdoc
2002 University of Chicago Postdoc
2000 University of Haifa, Israel Postdoc
2000 University of Bialystok, Poland Postdoc
1997 Jagiellonian University, Cracow, Poland PhD-Biology 
1993 Unversity of Lodz, Poland MS-Biology

View Full Publications List



Year Faculty Citation PMID
2021 Nicholas Kinney, Lin Kang, Ramu Anandakrishnan, Pawel Michalak, Harold "Skip" Garner

Kinney N, Kang L, Bains H, Lawson E, Husain M, Husain K, Sandhu I, Shin Y, Carter JK, Anandakrishnan R, Michalak P, Garner H. Ethnically biased microsatellites contribute to differential gene expression and glutathione metabolism in Africans and Europeans. PLoS One. 2021 Mar 25;16(3):e0249148. doi: 10.1371/journal.pone.0249148. eCollection 2021. PMID: 33765058.

2020 Pawel Michalak, Lin Kang

Gemmell NJ, Rutherford K, Prost S, Tollis M, Winter D, Macey JR, Adelson DL, Suh A, Bertozzi T, Grau JH, Organ C, Gardner PP, Muffato M, Patricio M, Billis K, Martin FJ, Flicek P, Petersen B, Kang L, Michalak P, Buckley TR, Wilson M, Cheng Y, Miller H, Schott RK, Jordan MD, Newcomb RD, Arroyo JI, Valenzuela N, Hore TA, Renart J, Peona V, Peart CR, Warmuth VM, Zeng L, Kortschak RD, Raison JM, Zapata VV, Wu Z, Santesmasses D, Mariotti M, Guigó R, Rupp SM, Twort VG, Dussex N, Taylor H, Abe H, Bond DM, Paterson JM, Mulcahy DG, Gonzalez VL, Barbieri CG, DeMeo DP, Pabinger S, Van Stijn T, Clarke S, Ryder O, Edwards SV, Salzberg SL, Anderson L, Nelson N, Stone C; Ngatiwai Trust Board. The tuatara genome reveals ancient features of amniote evolution. Nature. 2020 Aug;584(7821):403-409. PMID: 32760000.

2020 Pawel Michalak, Lin Kang

Budnick JA, Sheehan LM, Benton AH, Pitzer JE, Kang L, Michalak P, Roop RM 2nd, Caswell CC. Characterizing the transport and utilization of the neurotransmitter GABA in the bacterial pathogen (Brucella abortus). PLoS One. 2020 Aug 26;15(8):e0237371. PMID: 32845904.

2020 Pawel Michalak, Lin Kang

Pinzari CA, Kang L, Michalak P, Jermiin LS, Price DK, Bonaccorso FJ. Analysis of genotype sequence data reveals the origin and evolutionary separation of Hawaiian hoary bat populations. Genome Biol Evol. 2020 Aug 27:evaa137. PMID: 32853363.

2020 Ramu Anandakrishnan, Tiffany Carpenetti, Pawel Michalak, Lin Kang, Nicholas Kinney, Arben Santo, John Anstrom, Harold "Skip" Garner, Robin Varghese

Anandakrishnan R, Carpenetti TL, Samuel P, Wasko B, Johnson C, Smith C, Kim J, Michalak P, Kang L, Kinney N, Santo A, Anstrom J, Garner HR, Varghese RT. DNA sequencing of anatomy lab cadavers to provide hands-on precision medicine introduction to medical students. BMC Med Educ. 2020 Nov 16;20(1):437. PMID: 33198737.

2020 Lin Kang, Pawel Michalak

Budnik JA, Sheehan LM, Ginder M, Failor K, Perkowski J, Pinto J, Kohl K, Kang L, Michalak P, Luo L, Heindl J and Caswell C. A central role for the transcriptional regulator VtlR in small RNA-mediated gene regulation in Agrobacterium tumefaciens. Scientific Reports. 2020 Sep 11;10(1):14968. PMID: 32917931.

2019 Lin Kang, Pawel Michalak, Ramu Anandakrishnan, Robin Varghese, Nicholas Kinney, Harold "Skip" Garner

Kinney N, Titus-Glover K, Wren JD, Varghese RT, Michalak P, Liao H, Anandakrishnan R, Pulenthiran A, Kang L, Garner HR. CAGm: a Repository of Germline Microsatellite Variations in the 1000 Genomes Project, Nucleic Acids Res. 2019 Jan 8;47(D1):D39-D45. PMID: 30329086.

2019 Lin Kang, Pawel Michalak, Harold "Skip" Garner, Beverly Rzigalinski, James Mahaney

Kang L, Rashkovetsky E, Michalak K, Garner HR, Mahaney JE, Rzigalinski BA, Korol A, Nevo E, Michalak P. Genomic divergence and adaptive convergence in Drosophila simulans from Evolution Canyon, Israel. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11839-11844. PMID: 31127048.

2019 Nicholas Kinney, Lin Kang, Ramu Anandakrishnan, Robin Varghese, Pawel Michalak, Harold "Skip" Garner

Kinney N, Kang L, Eckstrand L, Pulenthiran A, Samuel P, Anandakrishnan R, Varghese RT, Michalak P, Garner HR. Abundance of ethnically biased microsatellites in human gene regions. PLoS One. 2019 Dec 12;14(12):e0225216. PMID: 31830051.

2019 Lin Kang, Pawel Michalak

Van Hoek ML, Prickett MD, Settlage RE, Kang L, Michalak P, Vliet KA, Bishop B. The Komodo dragon (Varanus komodoensis) genome and identification of innate immunity genes and clusters. BMC Genomics. 2019 Aug 30;20(1):684. PMID: 31470795.

2019 Pawel Michalak

Aggarwal DD, Rybnikov S, Cohen I, Frenkel Z, Rashkovetsky E, Michalak P, Korol AB. Desiccation-induced changes in recombination rate and crossover interference in Drosophila melanogaster: evidence for fitness-dependent plasticity. Genetica. 2019 Jun 25. [Epub ahead of print] PMID: 31240599.

2019 Lin Kang, Pawel Michalak

Lang JJ, Snyder RJ, Clapsadl MD, Michalak P, Kang L, Pérez-Fuentetaja A. Morphometric differentiation and gene flow in emerald shiners (Notropis atherinoides) from the lower Great Lakes and the Niagara River. Journal of Great Lakes Research. 2019 Apr;45(2):324-332. DOI: 10.1016/j.jglr.2018.12.002.

2018 Lin Kang, Pawel Michalak, Harold "Skip" Garner

Velmurugan KR, Michalak P, Kang L, Fonville NC, Garner HR. Dysfunctional DNA repair pathway via defective FANCD2 gene engenders multifarious exomic and transcriptomic effects in Fanconi anemia. Mol Genet Genomic Med. 2018 Nov;6(6):1199-1208. PMID: 30450770.

2018 Lin Kang, Pawel Michalak, Harold "Skip" Garner

Michalak P, Kang L, Schou MF, Garner HR, Loeschcke V. Genomic signatures of experimental adaptive radiation in Drosophila. Mol Ecol. 2019 Feb;28(3):600-614. PMID: 30375065.

2018 Lin Kang, Pawel Michalak

Michalak P, Kang L. Unique divergence of the breast cancer 2 (BRCA2) gene in Neanderthals. Hereditas. 2018 Nov 3;155:34. PMID: 30410429.

2018 Lin Kang, Pawel Michalak

Budnick JA, Sheehan LM, Kang L, Michalak P, Caswell CC. Characterization of three small proteins in Brucella abortus linked to fucose utilization. J Bacteriol. 2018 Aug 24;200(18). pii: e00127-8. PMID: 29967118.

2017 Pawel Michalak, Harold "Skip" Garner

Kang L, Garner HR, Price DK, Michalak P. A Test for Gene Flow among Sympatric and Allopatric Hawaiian Picture-Winged Drosophila. J Mol Evol. 2017 Jun;84(5-6):259-66. PMID: 28492967.

2017 Lin Kang, Pawel Michalak

Michalak P, Kang L, Ciparis S, Henley W, Jones J, Phipps A, Hallerman E. Freshwater mussels exposed to arsenic and sulfate show contrasting patterns of gene expression. In Organismal and Molecular Malacology (Ed. S. Ray). 2017 Aug 16:99-117. DOI: 10.5772/67674.

2017 Lin Kang, Pawel Michalak

Yablonovitch AL, Fu J, Li K, Mahato S, Kang L, Rashkovetsky E, Korol AB, Tang H, Michalak P, Zelhof AC, Nevo E, Li JB. Regulation of gene expression and RNA editing in Drosophila adapting to divergent microclimates. Nat Commun. 2017 Nov 17;8(1):1570. PMID: 29146998.

2017 Lin Kang, Pawel Michalak

Kang L, George P, Price DK, Sharakhov I, Michalak P. Mapping Genomic Scaffolds to Chromosomes Using Laser Capture Microdissection in Application to Hawaiian Picture-Winged Drosophila. Cytogenet Genome Res. 2017;152(4):204-212. PMID: 29130948.