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Darren T Beck, PhD

Portrait of Darren Beck
Darren Beck, PhD
Discipline Chair for Cellular Biology and Physiology
Department/Discipline: Cell Biology and Physiology
Campus: Auburn
Office: 244
Fax: 334-442-4096
Email: Contact
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Research Interests

My early research focused on the beneficial effects of adjuvant therapies for the prevention and treatment of cardiovascular disease in clinical and pre-clinical populations concentrating on endothelial function/dysfunction and arterial stiffness on blood flow mechanics, myocardial oxygen demand, and left-ventricular wasted energy. To expand my research in aging and cardiovascular disease, I then focused on the differential effects of androgens and estrogens, specifically, testosterone replacement therapy in older hypogonadal males and the progression of benign prostatic hyperplasia, bone metabolism, and risk for developing cardiovascular disease.

Currently, my research focuses on the role of hormone dysregulation and the development of cognitive decline associated with aging and the progression of Alzheimer’s Disease (AD), related pathology and novel adjuvant therapies to prevent the progression of vascular disease associated with aging and the development of AD. Current projects include, ‘Regulation of Luteinizing Hormone to Prevent Cognitive Decline of Reproductive Senescence and Alzheimer’s Disease’, ‘Neurophysiological effects of whole coffee fruit concentrate in older adults with mild cognitive impairment: A fMRI Investigation’ and ‘Extra-virgin olive oil prevents MCI conversion to Alzheimer’s disease’. In addition, I continue to investigate the molecular environment of the prostate and the development of cancers. To this end, current collaborative projects include, ‘High-density lipoprotein cholesterol nanoparticle mimic for the early detection and treatment of prostate cancer’, ‘Novel engineered nanoparticle based drug delivery and biosensing assay system for in vivo prostate cancer treatment and monitoring’, and ‘Iatrogenic cardiac and skeletal muscle metabolic dysfunction in patients with breast cancer after chemotherapy and radiation treatment’

Selected Publications

Year Faculty Citation PMID
2020 Darren Beck

Fox CD, Garner CT, Mumford PW, Beck DT, Roberts MD. Higher Doses of a Green Tea-Based Supplement Increase Post-Exercise Blood Flow Following an Acute Resistance Exercise Bout in Recreationally Resistance-Trained College-Aged Men. J Int Soc Sports Nutr. 2020 May 27;17(1):27. PMID: 32460790.

2020 Darren Beck

Roberts MD, Young KC, Fox CD, Vann CG, Roberson PA, Osburn SC, Moore JH, Mumford PW, Romero MA, Beck DT, Haun CT, Badisa VLD, Mwashote BM, Ibeanusi V, Kavazis AN. An optimized procedure for isolation of rodent and human skeletal muscle sarcoplasmic and myofibrillar proteins. J Biol Methods. 2020 Feb 24;7(1):e127. PMID: 32201709.

2020 Darren Beck

Sefton J, Lyons K, Beck D, Haun C, Romero M, Mumford P, Roberson P, Young K, Roberts M, McAdam J. Markers of bone health and impact of whey protein supplementation in Army Initial Entry Training Soldiers. Nutrients/ 2020 Jul 26;12(8):2225. PMID: 32722609.

2020 Darren Beck

Vann CG, Roberson PA, Osburn SC, Mumford PW, Romero MA, Fox CD, Moore JH, Haun CT, Beck DT, Moon JR, Kavazis AN, Young KC, Badisa VLD, Mwashote BM, Ibeanusi V, Singh RK, Roberts MD. Skeletal Muscle Myofibrillar Protein Abundance Is Higher in Resistance-Trained Men, and Aging in the Absence of Training May Have an Opposite Effect. Sports (Basel). 2020 Jan 10;8(1). pii: E7. PMID: 31936810.

2020 Darren Beck

Vann CG, Osburn SC, Mumford PW, Roberson PA, Fox CD, Sexton CL, Johnson MR, Johnson JS, Shake J, Moore JH, Millevoi K, Beck DT, Badisa VLD, Mwashote BM, Ibeanusi V, Singh RK, Roberts MD. Skeletal Muscle Protein Composition Adaptations to 10 Weeks of High-Load Resistance Training in Previously-Trained Males. Front Physiol. 2020 Mar 26;11:259. PMID: 32292355.

2017 Darren Beck

Mobley CB, Mumford PW, McCarthy JJ, Miller ME, Young KC, Martin JS, Beck DT, Lockwood CM, Roberts MD. Whey protein-derived exosomes increase protein synthesis in C2C12 myotubes. J Dairy Sci. 2017 Jan;100(1):48-64. PMID: 28341051.

2017 Darren Beck

Beck DT. Appendix C: Electrocardiogram Interpretation. In: American College of Sports Medicine. ACSM's Guidelines for Exercise Testing and Prescription (10th Edition). Riebe D, Ehrman J, Magal M, Liguori G (Eds.). Lippincott Williams; 2017 Feb 10: p. 405-32.

2017 Darren Beck

Beck DT. Appendix A: Common Medications. In: American College of Sports Medicine. ACSM's Guidelines for Exercise Testing and Prescription (10th Edition). Riebe D, Ehrman J, Magal M, Liguori G (Eds.).  Lippincott Williams; 2017 Feb 10: p. 405-32.

2016 Darren Beck

Mobley CB, Kephart WC, Fox CD, Conover CF, Beggs LA, Otzel DM, Balaez A, Yarrow JF, Borst SE, Beck DT, Roberts MD. Effects of testosterone on markers of skeletal muscle ribosome biogenesis. Andrologia. 2016 Jan 19.

2015 Darren Beck

Beggs LA, Ye F, Ghosh P, Beck DT, Conover CF, Balaez A, Miller JR, Philips EG, Zheng N, Williams AA, Aguirre JI, Wronski TJ, Bose PK, Borst SE, Yarrow JF. Sclerostin inhibition prevents spinal cord injury induced bone loss. Journal of Bone and Mineral Research. 2015 Apr;30(4):681-9.

2015 Darren Beck

Beck DT, Casey DP, Martin JS, Sardina PD, Braith RB. Enhanced external counterpulsation reduces indices of central blood pressure and myocardial oxygen demand in patients with left ventricular dysfunction. Clinical and Experimental Physiology and Pharmacology. 2015; 42(4): 315-320.

2015 Darren Beck

Delmonico MJ, Beck DT. The current understanding of sarcopenia: emerging tools and interventional possibilities. American Journal of Lifestyle Medicine. 2015 Jul 15. doi: 10.1177/1559827615594343.