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Jack Pledger, PhD

Jack Pledger, PhD

Associate Dean for Biomedical Affairs and Research
Campus: 
Carolinas Campus
Office: 

145

Department/Discipline: 
Phone: 
864-327-9896
Fax: 
864-804-6986
Email: 
pledger [at] gibbscc.org

Publications

Year Published Faculty Citation PMID
2016

Sharma S, Pledger WJ.  The non-canonical functions of p27kip1 in normal and tumor biology. Cell cycle. 2016 May 2;15(9):1189-201.

27082696
2015

Sharma S, Ma L, Pledger WJ.  p27kip inhibits the cell cycle through non-canonical G1/S phase specific gate keeper mechanism. Cell Cycle. 2015 Dec 17;14(24):3954-64.

26697844
2014

Wells KJ, Lima DS, Meade CD, Munoz-Antonia T, Scarinci I, McGuire A, Gwede CK, Pledger WJ, Partridge E, Lipscomb J, Matthews R, Matta J, Flores I, Weiner R, Turner T, Miele L, Wiese TE, Fouad M, Moreno CS, Lacey M, Christie DW, Price-Haywood EG, Quinn GP, Coppola D, Sodeke SO, Green BL, Lichtveld MY. Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities. Eval Progam Plann. 2014 Jun; 44:14-25.

24486917
2014

Zheng H, Chen L, Pledger WJ, Fang J, Chen J. p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression. Oncogene. 2014 Feb 6; 33(6):734-44.

23376847
2013

Bagui TK, Sharma SS, Ma L, Pledger WJ. Proliferate status regulates HDAC11 mRNA abundance in nontransformed fibroblasts. Cell Cycle. 2013 Nov 1; 23(21):3433-41.

24047695
2013

Fu W, Sharma SS, Ma L, Chu B, Bui MM, Reed D, Pledger WJ. Apoptosis of osteosarcoma cultures by the combination of cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor. Cell Death Dis. 2013 Mar 28; 4:e566.

23538447
2013

Hodul PJ, Dong Y, Husain K, Pimiento JM, Chen J, Zhang A, Francois R, Pledger WJ, Coppola D, Sebti SM, Chen DT, Malafa MP. Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. PLoS One. 2013;8(2):e52526.

2339354