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Harold "Skip" Garner, PhD

Harold "Skip" Garner, PhD

Associate Vice Provost for Research Development
Campus: 
Virginia Campus
Office: 

Knollwood 139

Department/Discipline: 
Phone: 
214-924-8364
Fax: 
540-231-2001
Email: 
sgarner [at] vt.vcom.edu
Curriculum Vitae: 

Skip received his BS in Nuclear Engineering at the University of Missouri - Rolla in 1976. Skip received a Ph.D. in plasma physics from the University of Wisconsin, Madison in 1982. He also holds an honorary professional engineering degree.

Skip worked for 12 years at General Atomics in La Jolla, California, where he conducted experimental and theoretical research for the Department of Energy at international fusion research facilities. In the last 6 years at General Atomics, he was a founding member of “The Institute”, an internal think tank, where he developed artificial intelligence/expert systems, new particle accelerators, high temperature superconductors, stealth/defense technologies and biology software and instrumentation.

From 1994 to 2009, at the University of Texas Southwestern Medical Center, Skip held the P. O’B. Montgomery, M.D., Distinguished Chair, was a Professor of Biochemistry and Internal Medicine and a founding member of the Division of Translational Research (DTR). 

In 2009, Skip moved to Virginia Tech, where he is currently the Executive Director, office of Medical Informatics, Translation, Training and Ethics (MITTE) and a professor of biological science, computer science and medicine. 

In 2016, Skip also became a Professor of Biomedicine, Edward Via College of Osteopathic Medicine (VCOM) and Executive Director, Primary Care Research Network and the Center for Bioinformatics and Genetics.

He sits on numerous corporate advisory boards and advises for numerous governmental agencies. He is also the founder of several companies - Helix, BioAutomation, Light Biology (sold to Nimblegen, acquired by Roche), Orbit Genomics, Heliotext, Quanta Lingua and Comperity.

Skip has published over 200 peer-reviewed manuscripts, 10 books/book chapters and has over 30 issued and pending patents, US and International.

Education

1994 University of Missouri, Rolla PE - Nuclear Engineering (honorary)
1982 University of Wisconsin, Madison PhD - Plasma Physics
1978 University of Wisconsin, Madison MS - Nuclear Engineering
1976 University of Missouri, Rolla BS - Nuclear Engineering

Awards and Honors

  • Fellow of the American Institute for Medical and Biological Engineering
  • Charter member of the Academy of the School of Mines and Metallurgy and Order of the Golden Shillelagh, University of Missouri - Rolla
  • Postdoctoral Mentor of the Year, UT Southwestern Medical Center 2008
  • Fellow of the Virginia Tech Honors Residence College

Current Professional Organizations

  • AAAS, AACR, VaBio

Current Research Projects

  • Diagnostic experiences of 3rd and 4th year medical students on clinical rotations
  • Event Tracking to Solve Medical Communication Gaps in the Dermatology Offices
  • Evidence-based optimization of the Bredesen protocol for diminished mental capacity
  • Identifying and quantifying the level of questionable “abstract publications” at scientific meetings

Publications

Year Published Faculty Citation PMID
2019

Kinney N, Titus-Glover K, Wren JD, Varghese RT, Michalak P, Liao H, Anandakrishnan R, Pulenthiran A, Kang L, Garner HR. CAGm: a Repository of Germline Microsatellite Variations in the 1000 Genomes Project, Nucleic Acids Res. 2019 Jan 8;47(D1):D39-D45. PMID: 30329086.

30329086
2019

Stanco KM, Prater MR, Wubah A, Sumpter C, Rawlins F, Garner HR. Improving Medical Education by Coupling Basic Science Lectures and Clinical Rotations via ICD Codes. J Am Osteopath Assoc. 2019 Apr 1;119(4):251-256. PMID: 30907964.

30907964
2019

Kang L, Rashkovetsky E, Michalak K, Garner HR, Mahaney JE, Rzigalinski BA, Korol A, Nevo E, Michalak P. Genomic divergence and adaptive convergence in Drosophila simulans from Evolution Canyon, Israel. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11839-11844. PMID: 31127048.

31127048
2019

Anandakrishnan R, Varghese R, Kinney N, Garner HR. Estimating the number of genetic mutations (hits) required for tumorigenesis based on the distribution of somatic mutations. PLoS Comput Biol. 2019 Mar 7;15(3):e1006881. PMID: 30845172.

30845172
2019

Dash S, Kinney N, Varghese R, Garner H, Feng W, Anandakrishnan R. Differentiating between cancer and normal tissue samples using multi-hit combinations of genetic mutations. Sci Rep. 2019 Jan 30;9(1):1005. PMID: 30700767.

30700767
2018

Michalak P, Kang L, Schou MF, Garner HR, Loeschcke V. Genomic signatures of experimental adaptive radiation in Drosophila. Mol Ecol. 2019 Feb;28(3):600-614. PMID: 30375065.

30375065
2018

Velmurugan KR, Michalak P, Kang L, Fonville NC, Garner HR. Dysfunctional DNA repair pathway via defective FANCD2 gene engenders multifarious exomic and transcriptomic effects in Fanconi anemia. Mol Genet Genomic Med. 2018 Nov;6(6):1199-1208. PMID: 30450770.

30450770
2018

Kinney N, Larsen TR, Kim DM, Varghese RT, Poelzing S, Garner HR, AlMahameed ST. Whole Exome Sequencing Reveals Microsatellites DNA Markers for Response to Dofetilide Initiation in Patients with Persistent Atrial Fibrillation, A Pilot Study.  Clin Cardiol. 2018 Apr 19. PMID: 29671888.

29671888
2018

Wubah AA, Yankson JA, Sumpter C, Rawlins F, Sutphin D, Menier K, Garner HR. Evaluation of an ICD Logging System to Supplement an EMR in a Sub-Saharan Country. Journal of Hospital Administration, 2018;7(2).

2017

Velmurugan KR, Varghese RT, Fonville NC, Garner HR. High-depth, high-accuracy microsatellite genotyping enables precision lung cancer risk classification. Oncogene. 2017 Jul 31. Epub ahead of print. PMID: 28759038.

28759038
2017

Rawlins F, Sumpter C, Sutphin D, Garner HR, Quantifying medical student clinical experiences via an ICD Code Logging App. Int J Med Inform. 2018 Mar;111:51-57. PMID: 29425634.

29425634
2017

Kang L, Garner HR, Price DK, Michalak P. A Test for Gene Flow among Sympatric and Allopatric Hawaiian Picture-Winged Drosophila. J Mol Evol. 2017 Jun;84(5-6):259-66. PMID: 28492967.

28492967
2017

Kinney N, Varghese RT, Anandakrishnan R, Garner HR. ZDHHC3 as a risk and mortality marker for breast cancer in African American Women. Cancer Informatics. 2017;16:1–6. PMID: 29276372.

29276372
2016

Kang L, Settlage R, McMahon W, Michalak K, Tae H, Garner HR, Stacy EA, Price DK, Michalak P. Genomic signatures of speciation in sympatric and allopatric Hawaiian picture-winged Drosophila. Genome Biol Evol. 2016 May 30;8(5):1482-8.

27189993
2016

Patidar PL, Motea EA, Fattah FJ, Zhou Y, Morales JC, Xie Y, Garner HR, Boothman DA. The Kub5-Hera/RPRD1B interactome: A novel role in preserving genetic stability by regulating DNA mismatch repair. Nucleic Acids Res. 2016 Feb 29;44(4):1718-31.

26819409
2016

Fonville NC, Velmurugan KR, Tae H, Vaksman Z, McIver LJ, Garner HR.  Genomic leftovers: identifying novel microsatellites, over-represented motifs and functional elements in the human genome.  Nature Sci Rep. 2016 Jun 9;6:27722.

27278669
2015

Michalak K, Maciak S, Kim YB, Santopietro G, Oh JH, Kang L, Garner HR, Michalak P. Nucleolar dominance and maternal control of 455 rDNA expression. Proc Biol Sci. 2015 Dec 7;282(1820):20152201.

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