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Current Research Projects

Sponsored Research Projects Currently Active

PI Name Project Title Funding Agency Campus
A Mental Health and Wellness App for Osteopathic Medical Students VCOM REAP Carolinas Campus
Antigenic and genetic evolution of influenza A viruses in the presence of preexisting homologous or heterologous immunity in the porcine model Center for One Health Research Auburn Campus
Biochemical Effects of Osteopathic Manipulation on Neuronal Function and Survival American Osteopathic Assocation Virginia Campus
Biomechanical basis of pediatric mTBI due to sports related concussion NIH (Virginia Tech) Virginia Campus
Biomechanics, biomarkers, and MRI: A three-pronged approach to predicting anterior cruciate ligament (ACL) rupture Auburn University Auburn Campus
Chelation therapy salvages the DNA damaging effects of lead and cadmium on endothelial cells VCOM REAP
Closed Loop Referral System VCOM REAP Carolinas Campus
Detecting muscle tissue and bone mineral content loss, growth, and maintenance at the cellular, segmental, and total-body level using bioimpedance spectroscopy using the SOZO and SFB7 devices ImpediMed Auburn Campus
Development and pharmacological characterization of mechanistically distinct NMDA receptor allosteric modulators American Heart Association Virginia Campus
Development of an eDNA protocol for detecting candy, variegate, and Kanawha darters Virginia Department of Game and Inland Fisheries Virginia Campus
Development of an Image-Guided Focused Ultrasound System for the Non-invasive Treatment of Injured Tendons VCOM REAP Virginia Campus
DOD-NCAA Grand Challenge: Concussion assessment, research and education (CARE) consortium 2 NCAA/DOD (Virginia Tech) Virginia Campus
Effect of maternal immune factors in shaping the infant gut microbiota NIH (Virginia Tech) Virginia Campus
Effects of Tolylfuanid on differentiating Cardiomyocytes VCOM REAP Carolinas Campus
Elucidating Mechanisms Modulated by NIK and Non-Canonical NF-κB Signaling in Colorectal Cancer Center for One Health Research Carolinas Campus
Epitranscriptome Dynamics upon Neuronal Activation: Novel Clues for Autism Pathology and Treatment Center for One Health Research Virginia Campus
Event Tracking to Solve Medical Communication Gaps in the Dermatology Offices VCOM REAP Virginia Campus
Evidence-based optimization of the Bredesen protocol for diminished mental capacity VCOM REAP Virginia Campus
Genomic characterization of the invasive Longhorned tick and its microbiota including the known pathogen, Theileria orientalis Center for One Health Research Virginia Campus
Genomics of two tree squirrels (Sciurus niger and S. Carolinensis) Virginia Museum of Natural History Virginia Campus
Hawaiian hoary bat conservation genetics: diet composition and population structure U.S. Geological Survey (Virginia Tech) Virginia Campus
Head impact biomechanics, concussion and osteopathic structural diagnosis and treatment American Osteopathic Association Virginia Campus
Iatrogenic Cardiac and Skeletal Muscle Metabolic Dysfunction in Patients with Breast Cancer after Combined Chemotherapy and Radiation Treatment VCOM REAP Auburn Campus
Identifying and quantifying the level of questionable “abstract publications” at scientific meetings Office of Research Integrity Virginia Campus
IGPOH-NR: An Integrative Genomics Platform for One Health – Noncoding RNAs VCOM REAP Virginia Campus
Impact of the Eustachian Tube Traction Technique on Post-Tonsillectomy Otalgia and Inflammation VCOM REAP Carolinas Campus
Improved Surveillance of Mosquito-borne Arboviruses in Alabama to Promote Effective Prevention Center for One Health Research Auburn Campus
Improving Platelet Storage with Cerium Oxide Nanoparticles VCOM REAP Virginia Campus
Isolation of antiviral and hemostatic factors from a naturally-occurring substance for treatment of viral infections and wounds of the dermis VCOM REAP Virginia Campus
M3 receptor inhibition synergistically enhances the anticancer activity of Cisplatin in Upper Gastrointestinal Cancers VCOM REAP Carolinas Campus
Mechanisms and Neuroprotective Effects of Triheteromeric NMDA Receptor Modulators Center for One Health Research Virginia Campus
Mechanisms of Mild Traumatic Brain Injury in Snow Sports VCOM REAP Virginia Campus
Mechanistic role of probiotic Lactobacillus reuteri in autoimmune lupus NIH (Virginia Tech) Virginia Campus
Microbiotic regulation of lupus nephritis Center for One Health Research Virginia Campus
Minute Calisthenics: A Daily, Habit-Based, Bodyweight Resistance Training Program VCOM REAP Auburn Campus
OR2T7: A prognostic marker and a potential therapeutic target for glioblastoma VCOM REAP Virginia Campus
Origin of the left common carotid artery from the brachiocephalic trunk results in increased endothelial thickening facilitated by bone marrow-derived hematopoietic progenitor cells VCOM REAP Carolinas Campus
Phage-peptide constructs as substitute for anti-cancer monoclonal antibody therapy: CD47-based model Center for One Health Research Auburn Campus
Post-surgical evaluation of the pelvic organ prolapse repairs using Cine-MRI VCOM REAP Auburn Campus
Quantification and qualification of stem cells after peripheral mobilization and harvest for orthopaedic point of care applications Arthrex Auburn Campus
Real time biofeedback Tai Chi training for knee osteoarthritis: A feasibility study NIH Auburn Campus
Role of skeletal muscle mitochondrial supercomplexes in exercise intolerance Providence VAMC Auburn Campus
Rural health best practices and community development HRSA (National Rural Health Association) Virginia Campus
Studying a Novel Mechanoceutics Treatment Strategy for Alzheimer ’s disease American Osteopathic Assocation Virginia Campus
The development and validation of a tool to assess non-cognitive akills in medical students using collaborative group testing AACOM Carolinas Campus
The effect of facial effleurage on acute rhinosinusitis AOA Carolinas Campus
The Effects of Light on Platelet Activity VCOM REAP Virginia Campus
The VCOM physician educator retention program Wythe-Bland Foundation Virginia Campus
Third-generation DNA sequencing approaches to rapid characterization of drinking water contamination in El Salvador, Honduras, and the Dominican Republic VCOM REAP Virginia Campus
VCOM fellowship for primary care transformation leaders HRSA Carolinas Campus
What is the extent to which people with MS utilize complementary and alternative medicine (CAM)? National Multiple Sclerosis Society (Harvard Medical School) Auburn Campus

Biomedical Research

PI Name Project Title Campus
A morphologic and T2 mapping score of the anterior cruciate ligament: Developing an outcome score for the evaluation of ACL reconstructions Auburn Campus
Acute effects of OxySport on lipolysis and basal metabolic rate, as well as chronic effects of OxySPORT on body composition in overweight, college-aged males Auburn Campus
Are quat disinfectants developmental or reproductive toxins? Virginia Campus
Biochemical effects of OMM at the cellular level Virginia Campus
Cerium Oxide nanoparticles in the treatment of traumatic brain injury Virginia Campus
Determining the mechanism behind the modulatory effects of sGP on macrophage and dendritic cell functions Carolinas Campus
Development of a nosocomial bacterial vaccine Virginia Campus
Development of a point-of-care diagnostic kit for bacterial and viral pneumonia Virginia Campus
Developmental immunotoxicity of quat disinfectants Virginia Campus
Effect of boron on UV-induced skin cancer Virginia Campus
Effect of Ebola virus proteins, VP40 and secreted glycoprotein, upon macrophage differentiation, polarization and function Carolinas Campus
Effects of a ketogenic diet on bone health Auburn Campus
Effects of a purported thermogenic nutraceutical on changes in body composition and metabolism Auburn Campus
Effects of a subchronic ketogenic diet on skeletal muscle anabolic and catabolic signaling and adipose tissue signaling Auburn Campus
Effects of aging and nutrition on systemic stem cell content and physiological systems Auburn Campus
Effects of aging on systemic stem cell content and tissue functionality Auburn Campus
Effects of chronic testosterone and trenbolone enanthate on mature myostatin protein expression, skeletal muscle hypertrophy and satellite cell number Auburn Campus
Effects of chronic testosterone and trenbolone treatment on markers of skeletal muscle ribosome biogenesis Auburn Campus
Effects of egg protein + colostrum blends on immune cell recovery after dexamethasone-induced immunosuppression in rats Auburn Campus
Evaluation of respiratory syncytial virus pathogenesis Virginia Campus
Examining brain changes associated with a 30-day diet intervention (Whole30 Diet) Auburn Campus
Identification of transgenerational methylome changes from disinfectant Virginia Campus
Making intestinal organoids from induced pluripotent stem cells Carolinas Campus
Molecular mechanism of calcium transport in the heart Virginia Campus
Peripheral blood flow and exercise intolerance in pulmonary arterial hypertension Auburn Campus
Role of bone blood flow in bone loss following spinal cord injury Auburn Campus
Role of LGR5 signaling in skeletal muscle myoblast cells (skMDC) Carolinas Campus
Role of mitochondrial supercomplexes in PAH-induced exercise intolerance Auburn Campus
Role of skeletal muscle arterioles in exercise intolerance in idiopathic pulmonary arterial hypertension Auburn Campus
Screening tap water for development and reproductive toxicants Virginia Campus
Studying the efficacy of 'BCAA 3.1.2' on cycling performance, body composition, and immune system markers in elite cyclists over a training season Auburn Campus
The effect of Ebola virus proteins on T helper cell cytokine production Carolinas Campus
The effect of Ebola virus proteins, VP40 and sGP, on dendritic cells cytokine production, antigen presentation and T-cell activation Carolinas Campus
Variations of human vasculature Carolinas Campus

Clinical Research

PI Name Project Title Campus
Advancing Clinical Trials in Neonatal Opioid Withdrawal Syndrome (ACT NOW) Current Experience: Infant Exposure and Treatment Carolinas Campus
Atypical presentation of anterior ankle impingement in high jumper Virginia Campus
BATIDAV: Berberine adjunct treatment in Diabetes and vascular disease Virginia Campus
Detecting clinically significant cardiac abnormalities with pre-participation ECGs in college athletes Virginia Campus
Evaluation of lumbar puncture assist tool (LPAT) as a guide and training tool for successful lumbar puncture Carolinas Campus
Gender differences in the performance response to brace wear following ACL reconstruction Virginia Campus
Healing rate of LE ulcers using lymphatic techniques Carolinas Campus
Iron supplementation and performance in Division I Athletes Virginia Campus
Neonatal Illicit SubstanCe Exposure SC (NICE SC) Carolinas Campus
OMM diagnosis and treatment protocol for pregnant patients with back pain Carolinas Campus
Pediatric Lyme disease in Southwest Virginia Virginia Campus
Persistent Leg Pain in a Division I Basketball Player Virginia Campus
Pilot Study: Novel therapeutic strategies for treatment of Alzheimer disease Virginia Campus
PolyMA adjunct myeloma study Virginia Campus
Potential damage to nerve cells due to antibodies from a patient infected with Lyme disease Virginia Campus
The effect of osteopathic manipulative treatment on golf swings as measured by driver distances Carolinas Campus
The Efficacy and Safety of Human Lumbar Puncture assist Device (LPat) Carolinas Campus
Undetected Lyme disease in populations in Southwest Virginia, leading to delayed treatment and an increased incidence of chronic infection Virginia Campus
Valgus extension overload in young gymnast leading to osteochondritis dissecans of the left capitellum Virginia Campus
VCOM orthopedic sports medicine research initiative Auburn Campus
Vitamin D, Athletic Performance, and Health Virginia Campus
Voluntary cough as a treatment adjunct for counterstrain and other myofascial release techniques Carolinas Campus

Educational Research

PI Name Project Title Campus
A case study exploring the role of faculty in providing academic support to first- and second-year medical students. Virginia Campus
A comparison of medical student versus preceptor evaluation of clinical presentation skills Carolinas Campus
Are higher levels of intrinsic motivation related to higher levels of class performance in medical students? Carolinas Campus
Assessing the effectiveness of a Summer Enrichment Program in science and medicine for high school students Carolinas Campus
Creating a Professional Learning Community within Osteopathic Medical Students to foster a positive environment for peer-to-peer learning to improve retention rates Carolinas Campus
Diagnostic experiences of 3rd and 4th year medical students on clinical rotations Virginia Campus
From cadavers to cases: Using adult learning theories to enhance the laboratory environment Virginia Campus
Joint research project on necrotizing periodontal diseases in children Virginia Campus
Reliability of standardized patient graders versus faculty in a clinical procedural skills assessment in undergraduate medical education Virginia Campus
The effect of required academic support services on academic performance in the medical school setting Virginia Campus
The effects of osteopathic medical school on medical student posture Carolinas Campus
Utilizing early pediatric growth to predict the incidence of obesity at 7 years of age Carolinas Campus

Outreach and Other Research

PI Name Project Title Campus
Application of low cost prosthetic devices in Tegucigalpa, Honduras and surrounding areas Virginia Campus
Assessment of hygiene, water accessibility and sanitation in Santa Rosa de Copan, Honduras Virginia Campus
Determination of weaning foods used in the Dominican Republic, El Salvador and Honduras and the impact they have upon gastrointestinal parasitic infections in children Virginia Campus
Effectiveness of educational intervention in medically underserved communities Carolinas Campus
Effectiveness of health fairs in the Hispanic community Carolinas Campus
El Salvador: Exploring barriers to cervical cancer screening Carolinas Campus
Health status of populations in coal mining communities in the Appalachian region of Virginia and West Virginia Virginia Campus
Infectious disease assessment in the Caribbean and Central America Virginia Campus
PLAY - Promoting Lifelong Activity in Youth - an Osteopathic Approach to Engage Children in Physical Activity using an Integrative Family-Centered Approach Carolinas Campus
Preventive health: Evaluating core strength, symmetry, somatic dysfunction, and injury prevalence among emergency medical personnel Carolinas Campus
Rates of heart disease, cancer, diabetes and obesity in coal production communities in economically distressed areas of Virginia and West Virginia in central Appalachia Virginia Campus
Retrospective study of amputee patient demographic assessment in Tegucigalpa, Honduras and surrounding areas Virginia Campus
Risk factors for cervical cancer in Tegucigalpa, Honduras Carolinas Campus
Survey of clinical encounters and demographics in Veron, Dominican Republic Virginia Campus
Survey of nutrition program support and community development in Honduras Virginia Campus
The prevalence of dermatological infections found in the Dominican Republic, El Salvador, Honduras and rural Appalachia Virginia Campus
VCOM community environment assessment in community centers and an orphanage in Tegucigalpa, Honduras Virginia Campus